The paper “Structure determination of high-energy states in a dynamic protein ensemble”
that describes methodology to combine pseudo contacts shifts and CPMG relaxation
dispersion experiments to determine high-energy protein structures has appeared in
Congratulations to first-author John Stiller
and everyone else involved on a great story. The project was a collaboration
with Doug Theobald at
Brandeis University and
Daniel Häussinger’s lab at the University of Basel, Switzerland.
Click on this link
for the full article and/or read the
Research Briefing: ‘Determining the structure of fleeting protein states’.
Christiana Ntangka joins the lab as a graduate studentin the Biochemistry & Biophysics (BCPB) program. Welcome to the Kern-Lab-Family!
Joseph graduated last weekend with a BS in Biology and Biochemistry and a MS in Biology.
He finished his research project in the Kern lab with an excellent thesis talk and we are
sure he is fully prepared for his next step as a graduate student.
Congratulations, enjoy your break, and good luck in your PhD journey!
Our paper entitled “How directed evolution reshapes the energy landscape in an enzyme to boost catalysis” has appeared ahead of print on the Science website. In collaboration with the Hilvert lab @ ETH Zurich, we show the molecular origins of how directed evolution resulted in the fastest Kemp eliminase to-date. Congratulations to all involved!
Zachary Boswell started as a postdoctoral fellow
after graduating from Texas Tech University. Welcome to the Kern Lab!