How directed evolution reshapes the energy landscape in an enzyme to boost catalysis

Renee Otten
23 November 2020

Our paper entitled “How directed evolution reshapes the energy landscape in an enzyme to boost catalysis” has appeared ahead of print on the Science website. In collaboration with the Hilvert lab @ ETH Zurich, we show the molecular origins of how directed evolution resulted in the fastest Kemp eliminase to-date. Congratulations to all involved!